Free Water as a Marker of Early Small Vessel Disease in Healthy Aging
Even in subjects with subtle, clinically silent, cerebral white matter changes, increases in FW could be observed compared to individuals without those changes. Therefore, FW might act as a sensitive marker at the earliest signs of SVD.
Authors
- Manuel Leitner (ORCID: https://orcid.org/0000-0001-5267-1103)
- Lukas Pirpamer (ORCID: https://orcid.org/0000-0002-4390-9703)
- Reinhold Schmidt (ORCID: https://orcid.org/0000-0002-6406-7584)
- Ofer Pasternak (ORCID: https://orcid.org/0000-0002-7078-6446)
- Marisa Koini (ORCID: https://orcid.org/0000-0002-1756-1379)
- Stefan Ropele (ORCID: https://orcid.org/0000-0002-5559-768X)
- Edith Hofer
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- University of Basel (CH)
- Medical University of Graz (AT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/ene.70094
- Citations
- 1
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Deutsche Forschungsgemeinschaft
- Austrian Science Fund