<scp>DNLA</scp> Delayed the Appearance of Learning and Memory Impairment of <scp>APP</scp>/<scp>PS1</scp> Mice: Involvement of <scp>mTOR</scp>/<scp>TFEB</scp>/v‐<scp>ATPase</scp> Signaling Pathway
These results unraveled that preventive administration of DNLA may delay the impairment of learning and memory in APP/PS1 mice. The molecular mechanism may be related to promoting the mTOR-TFEB-v-ATPase pathway.
Authors
- Jing Nie (ORCID: https://orcid.org/0000-0003-1002-5562)
- Qiye Li (ORCID: https://orcid.org/0000-0002-5993-0312)
- G. Luo
- Xuejia Liu (ORCID: https://orcid.org/0009-0007-8676-9134)
- Yajuan Wu
- Lisheng Li (ORCID: https://orcid.org/0000-0001-8696-4641)
- Bin Guo (ORCID: https://orcid.org/0000-0001-5199-5456)
Institutions
- Zunyi Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/cns.70300
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- Science and Technology Program of Guizhou Province