Effects of insulin‐induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes

Hypoglycaemia increased LVEF in all groups, but the increase diminished with longer disease duration and prior exposure to hypoglycaemia in type 1 diabetes, suggesting adaptation to recurrent hypoglycaemia. The increment in GLS observed in controls was blunted in people with diabetes. More research is needed to determine the clinical relevance of these findings.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-03-05
DOI
https://doi.org/10.1111/dom.16283
Citations
4
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
5.18
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article

Effects of insulin‐induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes

Clementine E. M. Verhulst, Cees J. Tack, Therese W. Fabricius, Anthonie L. Duijnhouwer et al.
4 citations
Diabetes Obesity and Metabolism
Diabetes Management and Research
5.18
article

Effects of insulin‐induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes

Clementine E. M. Verhulst, Cees J. Tack, Therese W. Fabricius, Anthonie L. Duijnhouwer, Ulrik Pedersen‐Bjergaard, Malene Wienberg, Cecilie H. Svensson, Bastiaan E. de Galan, Peter Lommer Kristensen
article en
4 citations

Abstract

Hypoglycaemia increased LVEF in all groups, but the increase diminished with longer disease duration and prior exposure to hypoglycaemia in type 1 diabetes, suggesting adaptation to recurrent hypoglycaemia. The increment in GLS observed in controls was blunted in people with diabetes. More research is needed to determine the clinical relevance of these findings.

Diabetes Obesity and MetabolismVol. 27(5)
University of Copenhagen (DK), Radboud University Nijmegen (NL), Novo Nordisk (Denmark) (DK), Maastricht University Medical Centre (NL), Radboud University Medical Center (NL), Maastricht University (NL), Nordsjællands Hospital (DK)
Good health and well-being
Openalex Percentile: Top 5%
Diabetes Management and Research
5.18
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Effects of insulin‐induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes — Clementine E. M. Verhulst, Cees J. Tack, et al. · Diabetes Obesity and Metabolism (2025) | TGRS Research Map | TGRS