Frailty Mediated the Associations of Fine Particulate Matter With Depression and Anxiety: Findings From the UK Biobank
Our findings suggest that both exposure to PM2.5 and frailty are associated with higher risk of depression and anxiety. The adverse associations between PM2.5 and depression/anxiety are partially mediated through frailty. Targeting frailty management could be a critical strategy for reducing the PM2.5-related psychiatric health burden.
Authors
- Yacong Bo
- Xiangying Suo
- Quanjun Lyu (ORCID: https://orcid.org/0000-0003-2978-522X)
- Yang Liu (ORCID: https://orcid.org/0000-0002-5961-1469)
- Jie You (ORCID: https://orcid.org/0000-0003-2374-8487)
- Junxi Zhang (ORCID: https://orcid.org/0000-0001-7982-3373)
- Jing Guo (ORCID: https://orcid.org/0009-0005-8497-9758)
Institutions
- Zhengzhou University (CN)
- Health Innovations (United States) (US)
- Henan Academy of Sciences (CN)
- Zhengzhou University of Science and Technology (CN)
- Third Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1093/gerona/glaf047
- Citations
- 3
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 3.60