Visual‐somatosensory integration as a novel behavioral marker of amyloid pathology

Here we provide support for the magnitude of VSI as a novel behavioral marker of AD-associated amyloid pathology given its significant association with an established, accurate, and reliable biomarker of AD pathology. Adults with normal cognition maintained the highest magnitude of VSI and brain amyloid negative scores. As cognitive impairment increased, the mean magnitude of VSI significantly decreased while amyloid probability scores (APS) increased. In fact, individuals with dementia revealed the lowest magnitude of VSI and the highest APS. Our research continues to emphasize the importance of successful multisensory integration in aging, where the establishment of future novel multisensory-based interventions aimed at preventing disability and optimizing independence could prove valuable.