Melanoma Cell Adhesion Molecule Plays a Pivotal Role in Proliferation, Migration, Tumor Immune Microenvironment, and Immunotherapy in Colorectal Cancer
The findings of this research suggest that MCAM impacts M1 macrophage polarization and enhances immunotherapy efficacy, underscoring its potential as a therapeutic target for colorectal cancer.
Authors
- Yumei Ning (ORCID: https://orcid.org/0009-0006-2292-7642)
- Qiu Zhao (ORCID: https://orcid.org/0000-0002-3230-6077)
- Haizhou Wang (ORCID: https://orcid.org/0000-0002-6079-9008)
- Yuntian Hong (ORCID: https://orcid.org/0000-0002-3546-1670)
- Haihang Nie
- Chao Yang (ORCID: https://orcid.org/0000-0003-3359-7483)
- Yali Yu (ORCID: https://orcid.org/0000-0001-9680-5783)
- Jun Lai (ORCID: https://orcid.org/0000-0002-3608-4985)
- Jingkai Zhou
- Xuelian Tang
- Fan Wang (ORCID: https://orcid.org/0009-0005-1207-7325)
- Jing Liu (ORCID: https://orcid.org/0000-0002-3255-3019)
Institutions
- Wuhan University (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Shanghai Electric (China) (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/cam4.70740
- Citations
- 1
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China