An Attention‐Aware Multi‐Task Learning Framework Identifies Candidate Targets for Drug Repurposing in Sarcopenia
Our novel approach effectively integrates multi-omics data to identify potential treatments for sarcopenia. The findings suggest that canagliflozin could be a promising therapeutic candidate for sarcopenia.
Authors
- Zhe Luo (ORCID: https://orcid.org/0000-0003-1384-1565)
- Xiao Zhang (ORCID: https://orcid.org/0000-0003-2169-2758)
- Hui Shen (ORCID: https://orcid.org/0000-0003-0335-6064)
- Hong‐Wen Deng (ORCID: https://orcid.org/0000-0002-0387-8818)
- Chuan Qiu (ORCID: https://orcid.org/0000-0001-6202-9229)
- Yun Gong
- Martin C. Nwadiugwu (ORCID: https://orcid.org/0000-0001-6788-8305)
- Shun‐Xing Liang (ORCID: https://orcid.org/0000-0001-9578-6533)
- Lin Xu (ORCID: https://orcid.org/0000-0002-7556-0235)
- Qing Tian (ORCID: https://orcid.org/0000-0001-9553-6278)
- Md. Selim Reza (ORCID: https://orcid.org/0000-0002-0540-5459)
- Anqi Liu (ORCID: https://orcid.org/0000-0002-3744-1585)
- Kuan‐Jui Su
Institutions
- Tulane University (US)
- Central South University (CN)
- The First People's Hospital of Shunde (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1002/jcsm.13661
- Citations
- 7
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 8.15
Funders
- National Institutes of Health