Is leukocyte scintigraphy recommended in periprosthetic knee infection diagnosis? A retrospective study of 92 total knee arthroplasties

Previously published studies on LS diagnostic performance report very variable results, probably due to the different and subjective PJI diagnostic criteria employed by each article. This is one of the first studies to employ the most recent PJI definitions and to demonstrate that LS may have a higher specificity and PPV than previously estimated. Therefore it represents a valid instrument in PJI diagnosis.

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Publication Details

Journal
The Knee
Published
2025-03-05
DOI
https://doi.org/10.1016/j.knee.2025.02.005
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Is leukocyte scintigraphy recommended in periprosthetic knee infection diagnosis? A retrospective study of 92 total knee arthroplasties

Stefano Zaffagnini, Cosimo Vasco, G Goracci, Monica Cosentino et al.
The Knee
Orthopedic Infections and Treatments
article

Is leukocyte scintigraphy recommended in periprosthetic knee infection diagnosis? A retrospective study of 92 total knee arthroplasties

Stefano Zaffagnini, Cosimo Vasco, G Goracci, Monica Cosentino, Maria Pia Neri, Mirco Lo Presti, Marco Minerba, Ludovica Solito, Davide Pellicanò
article en

Abstract

Previously published studies on LS diagnostic performance report very variable results, probably due to the different and subjective PJI diagnostic criteria employed by each article. This is one of the first studies to employ the most recent PJI definitions and to demonstrate that LS may have a higher specificity and PPV than previously estimated. Therefore it represents a valid instrument in PJI diagnosis.

The KneeVol. 54
Ospedale Santa Maria (IT), Istituto Ortopedico Rizzoli (IT)
Openalex Percentile: Top 93%
Orthopedic Infections and Treatments
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Is leukocyte scintigraphy recommended in periprosthetic knee infection diagnosis? A retrospective study of 92 total knee arthroplasties — Stefano Zaffagnini, Cosimo Vasco, et al. · The Knee (2025) | TGRS Research Map | TGRS