F-wave motor unit numbers do not change in diabetic polyneuropathy: does it indicate a pathophysiologic mechanism for generating F-waves?

Repeater F-wave parameters recorded from the upper extremity might indicate the presence of axon loss in DM-related polyneuropathy. However, F-MUNE failed to reveal axonal loss in diabetic polyneuropathy probably because of its length-dependent nature and the dominance of low-amplitude F-waves, which might be secondary to several yet unknown mechanisms, mainly related to sensory fiber dysfunction.

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Publication Details

Journal
Neurological Research
Published
2025-03-05
DOI
https://doi.org/10.1080/01616412.2025.2472828
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
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article

F-wave motor unit numbers do not change in diabetic polyneuropathy: does it indicate a pathophysiologic mechanism for generating F-waves?

Işıl Yazıcı Gençdal, Mehmet Barış Baslo, Nevin Dınççağ, Tuğrul Artuğ et al.
Neurological Research
Botulinum Toxin and Related Neurological Disorders
article

F-wave motor unit numbers do not change in diabetic polyneuropathy: does it indicate a pathophysiologic mechanism for generating F-waves?

Işıl Yazıcı Gençdal, Mehmet Barış Baslo, Nevin Dınççağ, Tuğrul Artuğ, İrem Ilgezdi, Nermi̇n Görkem Şi̇ri̇n, Ümmü Mutlu, Elif Kocasoy‐Orhan, Ali Emre Öge
article en

Abstract

Repeater F-wave parameters recorded from the upper extremity might indicate the presence of axon loss in DM-related polyneuropathy. However, F-MUNE failed to reveal axonal loss in diabetic polyneuropathy probably because of its length-dependent nature and the dominance of low-amplitude F-waves, which might be secondary to several yet unknown mechanisms, mainly related to sensory fiber dysfunction.

Neurological ResearchVol. 47(4)
Istanbul University-Cerrahpaşa (TR), Istanbul University (TR)
Good health and well-being
Openalex Percentile: Top 93%
Botulinum Toxin and Related Neurological Disorders
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