Exploring the Impact of Laboratory Reagents on Pharmacokinetic Profiling
Real-world data provided by haemophilia centres showed high congruence with WFH guidelines, although its sizable number not declaring reagent. WFH-recommended reagents did not significantly impact PK estimation. For rFVIII-PEG, reagents also did not impact PK estimation. Although usually not enough data were available to assess reagents that were unadvised by WFH.
Authors
- Dagmar M. Hajducek (ORCID: https://orcid.org/0009-0006-0365-6613)
- Emma Iserman (ORCID: https://orcid.org/0000-0001-7539-6490)
- Pierre Chelle (ORCID: https://orcid.org/0000-0002-0167-4774)
- Andrea N. Edginton (ORCID: https://orcid.org/0000-0002-9014-1653)
- Alfonso Iorio (ORCID: https://orcid.org/0000-0002-3331-8766)
Institutions
- University of Waterloo (CA)
- Impact (CA)
- McMaster University (CA)
Publication Details
- Journal
- Haemophilia
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1111/hae.70021
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sick Kids Foundation