What are we missing? Data from the Gonorrhoea Undetected Resistance Laboratory Study (GURLS)
This case-finding exercise provided reassurance that ceftriaxone-resistant <i>N. gonorrhoeae</i> in England is currently adequately detected through the existing UKHSA-enhanced surveillance activities. The current <i>penA</i> PCR is a useful tool in the fight to keep gonorrhoea a treatable infection; however, it requires expansion as it does not currently detect all <i>penA</i> alleles responsible for ceftriaxone resistance.
Authors
- Ross Harris (ORCID: https://orcid.org/0000-0003-3190-7281)
- Peter Muir (ORCID: https://orcid.org/0000-0003-0028-6005)
- Katie Thorley (ORCID: https://orcid.org/0000-0003-4322-2909)
- Michaela Day (ORCID: https://orcid.org/0000-0002-5089-2321)
- Laura Burgess Tornaletti (ORCID: https://orcid.org/0000-0003-2274-8792)
- Katy Sinka (ORCID: https://orcid.org/0000-0001-8596-0649)
- Anna Vickers
- Suzy Sun
- Rachel Pitt (ORCID: https://orcid.org/0000-0002-3524-5935)
- Mark Hopkins (ORCID: https://orcid.org/0000-0003-4744-8542)
- Hamish Mohammed (ORCID: https://orcid.org/0000-0002-2060-7286)
- Michelle Cole (ORCID: https://orcid.org/0000-0002-6707-6910)
- Monica Rebec
- Helen Fifer (ORCID: https://orcid.org/0000-0001-7756-403X)
- Hussain Ahmed (ORCID: https://orcid.org/0000-0003-3180-8208)
- Alan Lord
- Paul R. Grant (ORCID: https://orcid.org/0000-0003-2970-141X)
- Miriam O’Connor
- Soma N'Jai-Ndimbalan
- Kate Sibson
Institutions
- National Health Service (GB)
- North Bristol NHS Trust (GB)
- University Hospitals Birmingham NHS Foundation Trust (GB)
- Department of Health and Social Care (GB)
- University of Liverpool (GB)
- University of the West of England (GB)
- Environment Agency (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Aintree University Hospitals NHS Foundation Trust (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- University of Manchester (GB)
- National Institute for Health and Care Research (GB)
- Manchester University NHS Foundation Trust (GB)
- North West London Pathology (GB)
- UK Health Security Agency (GB)
- University College London (GB)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1136/sextrans-2024-056459
- Primary Topic
- Virology and Viral Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00