Ratifying the efficacy and safety of intensive induction chemotherapy for acute myeloid leukaemia by the Australasian Leukaemia & Lymphoma Group consensus approach
Idarubicin-based 7+3 induction with contemporary supportive care yields good safety and CR rates, including in midostaurin-treated FLT3-mutated patients. Survival outcomes for adverse-risk AML patients remain suboptimal.
Authors
- Michael Löw (ORCID: https://orcid.org/0000-0003-0077-640X)
- Shaun Fleming (ORCID: https://orcid.org/0000-0002-9734-5616)
- Amanda Tey
- Ashwini Bennett (ORCID: https://orcid.org/0000-0002-5788-6792)
- Paul Yeh (ORCID: https://orcid.org/0000-0002-4172-3614)
- Aditya Tedjaseputra (ORCID: https://orcid.org/0000-0001-6224-1940)
- Zane Kaplan (ORCID: https://orcid.org/0000-0001-7689-9997)
- Chong Chyn Chua (ORCID: https://orcid.org/0000-0002-2162-3288)
- Anastasios Nalpantidis
- S. Brown (ORCID: https://orcid.org/0000-0001-8112-933X)
- Gareth Peter Gregory (ORCID: https://orcid.org/0000-0002-4170-0682)
- Jake Shortt (ORCID: https://orcid.org/0000-0003-3185-6488)
- Pasquale L. Fedele (ORCID: https://orcid.org/0000-0002-2008-9749)
- Shahla Vilcassim
- Michael Gilbertson (ORCID: https://orcid.org/0000-0001-5275-374X)
- Danielle H. Oh (ORCID: https://orcid.org/0000-0001-9804-1449)
- Sanjeev Chunilal (ORCID: https://orcid.org/0000-0002-8172-7652)
- Stephen Opat (ORCID: https://orcid.org/0000-0002-0308-6458)
- George Grigoriadis
- Donna Gairns
Institutions
- King's College London (GB)
- Walter and Eliza Hall Institute of Medical Research (AU)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Northern Hospital (AU)
- Monash Health (AU)
- Alfred Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Internal Medicine Journal
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1111/imj.70010
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Haematology Society of Australia and New Zealand
- RCPA Foundation
- National Health and Medical Research Council