The Role of <scp>IL</scp>‐10–Producing Regulatory B Cells in Children With Primary Nephrotic Syndrome
Our study demonstrates that the numbers of B10 cells and their ability to produce IL-10 are decreased, leading to an imbalance in the Th17/Treg ratio and low IgG levels, which may then contribute to the pathogenesis of PNS.
Authors
- Shifang Dong
- Binbin Yang (ORCID: https://orcid.org/0009-0008-0036-8872)
- Xiongjun Tan
- Daoqi Wu
- Haiping Yang (ORCID: https://orcid.org/0000-0002-4245-9376)
- Mei Wang (ORCID: https://orcid.org/0000-0003-3292-1413)
- Mo Wang (ORCID: https://orcid.org/0000-0001-7004-3549)
- Qiu Li (ORCID: https://orcid.org/0000-0002-2481-7168)
- Xuelan Chen
- Gaofu Zhang (ORCID: https://orcid.org/0000-0003-4452-3674)
Institutions
- Shenzhen Bao'an District People's Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Nephrology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/nep.70008
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Key Research and Development Program of China