Antiangiogenic effect of circulating extracellular vesicles in acute coronary syndrome: Role of miR‐199a‐3p and miR‐125a‐5p

Circulating EVs play an important role in the control of angiogenesis. However, in the acute phase of NSTEMI, intercellular communication via EV is modified and loses its ability to generate new blood vessels. The loss of angiogenic capacity of EVs during NSTEMI may be an important player in the disease progression and outcomes.

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Publication Details

Journal
European Journal of Clinical Investigation
Published
2025-03-06
DOI
https://doi.org/10.1111/eci.70022
Citations
3
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
2.42

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article

Antiangiogenic effect of circulating extracellular vesicles in acute coronary syndrome: Role of miR‐199a‐3p and miR‐125a‐5p

Luis Ortega‐Paz, Carmen Fernández-Becerra, Manel Sabaté, Joaquim Bobí et al.
3 citations
European Journal of Clinical Investigation
Extracellular vesicles in disease
2.42
article

Antiangiogenic effect of circulating extracellular vesicles in acute coronary syndrome: Role of miR‐199a‐3p and miR‐125a‐5p

Luis Ortega‐Paz, Carmen Fernández-Becerra, Manel Sabaté, Joaquim Bobí, Ana García‐Álvarez, Ana Paula Dantas, Iolanda Lázaro, Núria Cortes-Serra, Salvatore Brugaletta, J Rodríguez, Francisco‐Rafael Jimenez‐Trinidad
article en
3 citations

Abstract

Circulating EVs play an important role in the control of angiogenesis. However, in the acute phase of NSTEMI, intercellular communication via EV is modified and loses its ability to generate new blood vessels. The loss of angiogenic capacity of EVs during NSTEMI may be an important player in the disease progression and outcomes.

European Journal of Clinical InvestigationVol. 55(7)
Instituto de Salud Carlos III (ES), Spanish National Centre for Cardiovascular Research (ES), Hospital Clínic de Barcelona (ES), Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES), Barcelona Institute for Global Health (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
Sociedad Española de Cardiología, Centres de Recerca de Catalunya, Agència de Gestió d'Ajuts Universitaris i de Recerca, Instituto de Salud Carlos III, European Regional Development Fund
Good health and well-being
Openalex Percentile: Top 13%
Extracellular vesicles in disease
2.42
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Antiangiogenic effect of circulating extracellular vesicles in acute coronary syndrome: Role of miR‐199a‐3p and miR‐125a‐5p — Luis Ortega‐Paz, Carmen Fernández-Becerra, et al. · European Journal of Clinical Investigation (2025) | TGRS Research Map | TGRS