Frequency‐specific network changes in mesial temporal lobe epilepsy: Analysis of chronic and transient dysfunctions in the temporo‐amygdala‐orbitofrontal network using magnetoencephalography
In mesial temporal lobe epilepsy, there may be abnormal connectivity between the hippocampus and the limbic system, which is involved in memory, cognition, and emotion. The changes in connectivity observed using magnetoencephalography may be implicated in cognitive and psychiatric problems experienced by patients with mesial temporal lobe epilepsy. Examining disruptions in the connectivity across brain regions in relation to epileptic activity could further the understanding of the pathophysiology of this debilitating condition and its impact on behavioral and emotional functions, among others.
Authors
- Jun Natsume (ORCID: https://orcid.org/0000-0002-2081-9449)
- Miki Hashida (ORCID: https://orcid.org/0009-0000-6930-4078)
- Yoshiki Ito (ORCID: https://orcid.org/0009-0006-0909-2353)
- Hiroyuki Yamamoto (ORCID: https://orcid.org/0000-0003-4742-7653)
- Ryuta Saito (ORCID: https://orcid.org/0000-0002-2484-1360)
- Satoshi Maesawa (ORCID: https://orcid.org/0000-0001-7518-0171)
- Takafumi Tanei (ORCID: https://orcid.org/0000-0002-9251-4230)
- Minoru Hoshiyama (ORCID: https://orcid.org/0000-0002-0499-4722)
- Tomotaka Ishizaki (ORCID: https://orcid.org/0000-0001-5346-6451)
- Takahiro Suzuki (ORCID: https://orcid.org/0009-0008-3086-4666)
Institutions
- Nagoya Medical Center (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1002/epi4.70018
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Japan Society for the Promotion of Science