Inhibition of <scp>MALT1</scp> Protease Attenuates Hepatic Sinusoidal Obstruction Syndrome by Modulating <scp>NRF2</scp> / <scp>HO1</scp> and <scp>NF‐κB</scp> Pathway
Thus, our findings demonstrate that MALT1 suppression dramatically reduces FOLFOX-induced inflammatory and fibrotic conditions by modulating the NF-κB activation, paving the way for innovative HSOS therapy approaches.
Authors
- Yogesh Chandra (ORCID: https://orcid.org/0000-0002-9697-2909)
- Sai Balaji Andugulapati (ORCID: https://orcid.org/0000-0002-7591-737X)
- Nidhi Sharma (ORCID: https://orcid.org/0000-0001-6422-8053)
Institutions
- Indian Institute of Chemical Technology (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Liver International
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1111/liv.70050
- Citations
- 2
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 1.59