Disentangling Organ‐Specific Roles of Farnesoid X Receptor in Bile Acid and Glucolipid Metabolism
Our study overcomes the limitations of traditional tissue-specific knockout models, providing a more comprehensive understanding of FXR's complex roles in metabolic homeostasis, encouraging the development of organ-specific FXR targeting strategy.
Authors
- Zhongzheng Tang (ORCID: https://orcid.org/0000-0002-8593-0383)
- Bei Liu (ORCID: https://orcid.org/0000-0003-4437-455X)
- Zheying Tao
- Chenyang Fu (ORCID: https://orcid.org/0009-0005-6550-9988)
- Changkun Li (ORCID: https://orcid.org/0000-0002-4277-830X)
- Tingting Cheng (ORCID: https://orcid.org/0000-0001-9452-6115)
- Guang Ning (ORCID: https://orcid.org/0000-0002-5754-7635)
- Tingting Li (ORCID: https://orcid.org/0009-0005-9090-1324)
- Li Zhang (ORCID: https://orcid.org/0000-0002-4891-7841)
- Shujie Wang (ORCID: https://orcid.org/0000-0001-8838-4771)
- Yanyun Gu (ORCID: https://orcid.org/0000-0002-4323-1648)
- Jie Yang (ORCID: https://orcid.org/0000-0001-5149-538X)
- Duanyi Hua
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Liver International
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1111/liv.70027
- Citations
- 6
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 6.27
Funders
- National Natural Science Foundation of China