Empagliflozin in resistant hypertension and heart failure with preserved ejection fraction: the EMPEROR-Preserved trial
In HFpEF, the prevalence of resHTN is high and is associated with frequently higher outcome rates compared with ctrHTN and uctrHTN. The treatment effect was not modified by hypertension categories. This indicates that in HFpEF, moderate modifications of blood pressure do not affect overall outcomes and treatment effects of empagliflozin.
Authors
- Stefan D. Anker (ORCID: https://orcid.org/0000-0002-0805-8683)
- Lucas Lauder (ORCID: https://orcid.org/0000-0003-1434-9556)
- Michael Böhm (ORCID: https://orcid.org/0000-0002-2976-2514)
- Martina Brueckmann (ORCID: https://orcid.org/0000-0003-1215-0746)
- Gerasimos S Filippatos (ORCID: https://orcid.org/0000-0002-5640-0332)
- Felix Mahfoud (ORCID: https://orcid.org/0000-0002-4425-549X)
- Elke Schueler (ORCID: https://orcid.org/0000-0002-5955-8303)
- Christoph Wanner (ORCID: https://orcid.org/0000-0001-9507-5301)
- Faiez M. Zannad (ORCID: https://orcid.org/0000-0001-7456-1570)
- Milton Packer (ORCID: https://orcid.org/0000-0003-1828-2387)
- Andrew J.S. Coats (ORCID: https://orcid.org/0000-0002-2771-4260)
- Javed Butler (ORCID: https://orcid.org/0000-0003-4267-6933)
- Subodh Verma (ORCID: https://orcid.org/0000-0002-4018-8533)
- Sibylle J. Hauske (ORCID: https://orcid.org/0000-0003-3319-3710)
- João Pedro Ferreira (ORCID: https://orcid.org/0000-0002-2304-6138)
- Stuart J. Pocock
Institutions
- Technische Hochschule Mannheim (DE)
- St. Michael's Hospital (CA)
- Inserm (FR)
- University of Mannheim (DE)
- Universidade do Porto (PT)
- University of Toronto (CA)
- National and Kapodistrian University of Athens (GR)
- Heidelberg University (DE)
- The Heart Research Institute (AU)
- Baylor University Medical Center (US)
- University Hospital of Basel (CH)
- Southern University Law Center (US)
- University of Mississippi (US)
- St Michael’s Hospital (IE)
- London School of Hygiene & Tropical Medicine (GB)
- Hospital Base (CL)
- Universitätsklinikum des Saarlandes (DE)
- Comprehensive Cancer Center Mainfranken (DE)
- Lung Institute (US)
- Baylor Medical Center at Garland (US)
- South African Heart Association (ZA)
- Boehringer Ingelheim (Egypt) (EG)
- German Centre for Cardiovascular Research (DE)
- St Michael's Hospital (GB)
- Institut des Vaisseaux et du Sang (FR)
- Centre d'Investigation Clinique Pierre Drouin (FR)
- Deutsches Herzzentrum München (DE)
- University Medical Centre Mannheim (DE)
- Berlin Heart (Germany) (DE)
- St Michaels Hospital (GB)
- French Clinical Research Infrastructure Network (FR)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1093/eurheartj/ehae938
- Citations
- 12
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 15.54