Data‐driven discovery of midlife cardiometabolic profile associated with incident early‐onset and late‐onset dementia
Cardiometabolic patterns characterised by relatively high liver enzyme levels or systemic inflammation were associated with increased risks of early-onset and late-onset dementia. Identification of high-risk subgroups according to distinct cardiometabolic patterns might help develop more precise strategies for dementia prevention regardless of apolipoprotein E (APOE) ε4 status.
Authors
- Yanqi Fu (ORCID: https://orcid.org/0000-0001-5443-3969)
- Xiao Tan (ORCID: https://orcid.org/0000-0003-3992-5812)
- Yuefeng Yu (ORCID: https://orcid.org/0000-0001-7439-4231)
- Ningjian Wang (ORCID: https://orcid.org/0000-0001-9591-6991)
- Yingli Lu (ORCID: https://orcid.org/0000-0002-5117-1614)
- Wenqi Shen (ORCID: https://orcid.org/0000-0001-5065-5361)
- Bin Wang (ORCID: https://orcid.org/0000-0002-4869-1352)
- Jie Li (ORCID: https://orcid.org/0000-0003-4400-2131)
- Jiang Li (ORCID: https://orcid.org/0000-0001-7394-9346)
- Lingli Cai
- Ying Sun (ORCID: https://orcid.org/0009-0008-5636-4350)
Institutions
- Uppsala University (SE)
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1111/dom.16292
- Citations
- 3
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Shanghai Municipal Health Commission
- Shanghai Municipal Human Resources and Social Security Bureau