Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome

Elevated serum IgE levels are associated with more severe clinical features in AIGAs syndrome, including increased infectious episodes, elevated inflammatory markers/immune markers, and multi-organ involvement, particularly skin. IgE serves as a marker of skin involvement and may indicate a potential response to glucocorticoid treatment.

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Publication Details

Journal
BMC Immunology
Published
2025-03-08
DOI
https://doi.org/10.1186/s12865-025-00696-6
Citations
2
Primary Topic
Urticaria and Related Conditions
Type
article
Field-Weighted Citation Impact
3.34
Controls
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article

Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome

Zhiyi He, Siqiao Liang, Qingliang Yu, Ni Chen et al.
2 citations
BMC Immunology
Urticaria and Related Conditions
3.34
article

Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome

Zhiyi He, Siqiao Liang, Qingliang Yu, Ni Chen, Xuemei Huang, Xiaona Liang, Hanlin Liang
article en
2 citations

Abstract

Elevated serum IgE levels are associated with more severe clinical features in AIGAs syndrome, including increased infectious episodes, elevated inflammatory markers/immune markers, and multi-organ involvement, particularly skin. IgE serves as a marker of skin involvement and may indicate a potential response to glucocorticoid treatment.

BMC ImmunologyVol. 26(1)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN), Tumor Hospital of Guangxi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 10%
Urticaria and Related Conditions
3.34
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Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome — Zhiyi He, Siqiao Liang, et al. · BMC Immunology (2025) | TGRS Research Map | TGRS