Mechanism of IRF8 on osteocyte apoptosis in steroid-induced osteonecrosis of the femoral head
IRF8 was enriched in the miR-181a-5p promoter to inhibit miR-181a-5p, thus promoting ZNF667 levels and increasing osteocyte apoptosis in SONFH, which may be a new theoretical basis for the treatment of SONFH.
Authors
- Yuanhui Wang (ORCID: https://orcid.org/0009-0001-1323-2041)
- Junwu Ye
- Tianmin Chang
- Xihai Zhang (ORCID: https://orcid.org/0000-0003-0933-1896)
- Daiqing Wei (ORCID: https://orcid.org/0000-0003-3061-4081)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Connective Tissue Research
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1080/03008207.2025.2472935
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.72