HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability
These results supported that HNRNPC regulate TFAP2A to promote the malignant progression and EMT of NSCLC. These findings connect m6A modification with EMT, providing a new perspective on the regulation of m6A modification in tumors.
Authors
- Qian Zhu (ORCID: https://orcid.org/0000-0003-1045-8819)
- Ke Wu (ORCID: https://orcid.org/0000-0002-7195-9601)
- Minghua Liao
- Jiayi Zhang (ORCID: https://orcid.org/0000-0002-5060-7762)
- Chunyu Li (ORCID: https://orcid.org/0000-0001-9437-9530)
- Xianming Zhang (ORCID: https://orcid.org/0000-0002-7503-4307)
- Rui Yang (ORCID: https://orcid.org/0000-0003-1801-6134)
- Ying-Chang Shi
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- The First People's Hospital of Guiyang (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1186/s12935-025-03660-x
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61