Link between iron-mediated lipid peroxidation and polycystic ovary syndrome (PCOS): exploring the genes underlying iron regulatory mechanism
The present study postulated the role of iron overload in trigger of ferroptosis following elevated lipid peroxidation and low peroxidase activity. Moreover, unveil the association of genes related to iron-regulating metabolism with etiology of underlying PCOS mechanism.
Authors
- Nasreen Rehmat Ullah
- Zertashia Akram (ORCID: https://orcid.org/0000-0003-3364-5510)
- Nayab Khalid
- Nasser J. Hayat
- Tehmina Mazhar
Institutions
- COMSATS University Islamabad (PK)
- Mari Petroleum Company (Pakistan) (PK)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1186/s13048-024-01562-6
- Citations
- 7
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 10.63