Examining the Outcomes of Palliative Oophorectomy of Ovarian Metastases in de-Novo Metastatic Colorectal Cancer and Its Association with RAS Mutation Status: Insights from a Single-Institution Perspective
Our study indicates that palliative oophorectomy in metastatic CRC is associated with better survival. Even patients who harbor mutated KRAS, which typically have more aggressive disease behavior, showed better survival outcomes with oophorectomy compared to systemic chemotherapy alone.
Authors
- Tala Alawabdeh (ORCID: https://orcid.org/0000-0001-5043-7428)
- Yosra Al-Masri
- Khair Hamo
- Rnad Khader
- Rim Turfa (ORCID: https://orcid.org/0000-0002-0962-3912)
- Teeba Mubaydeen
- Maram Al-Ya’goub
- Saif Alnassarwin
- Hadeel Masadeh
Institutions
- University of Jordan (JO)
- Mutah University (JO)
- King Hussein Cancer Center (JO)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/cmar.s495321
- Citations
- 1
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.05