Evaluation of Turmeric-Based Unani Formulation for Respiratory Tract Infection: Physicochemical Analysis, HPTLC Fingerprint Screening and Microbiological Studies

Respiratory tract infection is a significant non-communicable disease (NCD) that outcomes to significant impairment and fatality on a global scale. The highest number of fatalities occurs in poor and middle-income nations, including Oceania, South and Southeast Asia, the Middle East, and Africa. The World Health Organization (WHO) recognizes and values the significance of medicinal plants in public healthcare in developing countries. The Unani classical literature has several formulas for treating respiratory diseases. Sufoof Dama Haldi Wala is a specific formulation in the unani system using turmeric-based material. However, the quality criteria of this formulation have not been assessed yet. Hence, this work aimed to establish a standardized turmeric-based unani formulation by evaluating its physicochemical properties and doing HPTLC fingerprint screening. The quality requirements have been established by thorough physico-chemical examination. The microbial load test, aflatoxin, and In-vitro antioxidant activity were all within acceptable limits, and no microbes were detected in the produced turmeric based Unani formulation. The elemental analysis has also shown intriguing findings. Standardization of herbal drugs is crucial for ensuring quality control. It enhancing the safety and efficacy of drugs is crucial for delivering optimal treatment to the society. Obtained data for turmeric-based Unani formulation will serve as valuable benchmarks for ensuring the standards and quality control of formulation.