The Role of Central Inflammation in Postoperative Cognitive Dysfunction

Postoperative cognitive dysfunction is a typical complication, which can be referred to as POCD. This complication is common in elderly patients. Among them, POCD is mainly manifested in the function of patients with attention deficit and memory reduction after surgery, among which serious patients are prone to personality change, which affects their social behavior ability. In the context of the current era, the cause of POCD is not clear, combined with the results of most studies, it is found that central nervous inflammation, is a key factor affecting POCD. From the perspective of central inflammation, this paper analyzes the relationship between central inflammation and POCD, and discusses the mechanism of action, aiming at effectively preventing and treating POCD and providing a reference for subsequent research in related fields.

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Publication Details

Journal
Journal of Clinical and Nursing Research
Published
2025-03-06
DOI
https://doi.org/10.26689/jcnr.v9i2.9772
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

The Role of Central Inflammation in Postoperative Cognitive Dysfunction

Wenyuan Wang, Fang Yan
Journal of Clinical and Nursing Research
Intensive Care Unit Cognitive Disorders
article

The Role of Central Inflammation in Postoperative Cognitive Dysfunction

Wenyuan Wang, Fang Yan
article en

Abstract

Postoperative cognitive dysfunction is a typical complication, which can be referred to as POCD. This complication is common in elderly patients. Among them, POCD is mainly manifested in the function of patients with attention deficit and memory reduction after surgery, among which serious patients are prone to personality change, which affects their social behavior ability. In the context of the current era, the cause of POCD is not clear, combined with the results of most studies, it is found that central nervous inflammation, is a key factor affecting POCD. From the perspective of central inflammation, this paper analyzes the relationship between central inflammation and POCD, and discusses the mechanism of action, aiming at effectively preventing and treating POCD and providing a reference for subsequent research in related fields.

Journal of Clinical and Nursing ResearchVol. 9(2)
Nanjing Medical University (CN)
Openalex Percentile: Top 94%
Intensive Care Unit Cognitive Disorders
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The Role of Central Inflammation in Postoperative Cognitive Dysfunction — Wenyuan Wang, Fang Yan · Journal of Clinical and Nursing Research (2025) | TGRS Research Map | TGRS