Rare Association of Disseminated Cutaneous Leishmaniasis With Urethral Stricture: A Case Report

Leishmaniasis, a parasitic disease transmitted by sandflies, rarely presents with urogenital complications. This case highlights an unusual presentation of disseminated cutaneous leishmaniasis with urethral involvement. A 42-year-old male from an endemic region presented with macular-papules-nodular lesions on lips, nose, and tongue, accompanied by genital ulcers and urinary complications. Histopathological examination confirmed Leishmania parasites. The patient developed urethral stricture and urethrocutaneous fistula, which were managed successfully with systemic amphotericin B and staged urethroplasty. This case emphasizes the importance of considering leishmaniasis in the differential diagnosis of urogenital manifestations in endemic regions. The successful outcome demonstrates the effectiveness of combined medical and surgical management.

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Journal
Cureus
Published
2025-03-06
DOI
https://doi.org/10.7759/cureus.80179
Primary Topic
Research on Leishmaniasis Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Rare Association of Disseminated Cutaneous Leishmaniasis With Urethral Stricture: A Case Report

Nalin Srivastava, Vikas Kumar Panwar, Siddharta Saxena, Ankur Mittal et al.
Cureus
Research on Leishmaniasis Studies
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Rare Association of Disseminated Cutaneous Leishmaniasis With Urethral Stricture: A Case Report

Nalin Srivastava, Vikas Kumar Panwar, Siddharta Saxena, Ankur Mittal, Avin Singhal, Mehul Agarwal, Mohammed Taher Mujahid
article en

Abstract

Leishmaniasis, a parasitic disease transmitted by sandflies, rarely presents with urogenital complications. This case highlights an unusual presentation of disseminated cutaneous leishmaniasis with urethral involvement. A 42-year-old male from an endemic region presented with macular-papules-nodular lesions on lips, nose, and tongue, accompanied by genital ulcers and urinary complications. Histopathological examination confirmed Leishmania parasites. The patient developed urethral stricture and urethrocutaneous fistula, which were managed successfully with systemic amphotericin B and staged urethroplasty. This case emphasizes the importance of considering leishmaniasis in the differential diagnosis of urogenital manifestations in endemic regions. The successful outcome demonstrates the effectiveness of combined medical and surgical management.

CureusVol. 17(3)
Seema Dental College and Hospital (IN), All India Institute of Medical Sciences Rishikesh (IN)
Zero hunger
Openalex Percentile: Top 94%
Research on Leishmaniasis Studies
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