Integrative analysis of single-cell and bulk RNA sequencing reveals the oncogenic role of ANXA5 in gastric cancer and its association with drug resistance
This study offers novel insights into the subpopulations of malignant epithelial cells in GC and their roles in tumor progression. It provides a prognostic model and potential therapeutic targets to combat GC, contributing crucial understanding to the fundamental mechanisms of drug resistance in gastrointestinal cancers.
Authors
- Denggang Chen
- Guanghui Yu (ORCID: https://orcid.org/0000-0002-3174-1878)
- Hailang Wei
- Li Gong
- Tingting Zhang (ORCID: https://orcid.org/0000-0002-6575-6250)
- Peng Zhang (ORCID: https://orcid.org/0000-0002-2774-5534)
- Chen Bai
Institutions
- Hubei University of Medicine (CN)
- Minzu University of China (CN)
- Taihe Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-07
- DOI
- https://doi.org/10.3389/fimmu.2025.1562395
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00