Microbiological and clinical predictors of sepsis-associated encephalopathy in bloodstream infections: a retrospective cohort study

Coagulase-negative staphylococci is a significant risk factor for SAE development, but not for mortality. Advanced age, female gender, higher SOFA scores, and mechanical ventilation further contribute to SAE risk. Early identification and targeted management of pathogens, particularly methicillin-resistant Staphylococcus aureus, are crucial for improving SAE outcomes.