Characterization of carbapenem-resistant Klebsiella pneumoniae in bloodstream infections: antibiotic resistance, virulence, and treatment strategies

Our study reveals the multifaceted resistance and virulence profiles of CRKP in bloodstream infections and highlights the potential clinical value of berberine hydrochloride as an adjunctive therapeutic agent. These findings support further clinical investigations into incorporating traditional Chinese medicine to improve outcomes in patients with CRKP bloodstream infections.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-03-07
DOI
https://doi.org/10.3389/fcimb.2025.1541704
Citations
8
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
4.73
Controls
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article

Characterization of carbapenem-resistant Klebsiella pneumoniae in bloodstream infections: antibiotic resistance, virulence, and treatment strategies

Zeqi Li, Chenglin Zhong, Shaohua Lin, Xuejing Yang
8 citations
Frontiers in Cellular and Infection Microbiology
Antibiotic Resistance in Bacteria
4.73
article

Characterization of carbapenem-resistant Klebsiella pneumoniae in bloodstream infections: antibiotic resistance, virulence, and treatment strategies

Zeqi Li, Chenglin Zhong, Shaohua Lin, Xuejing Yang
article en
8 citations

Abstract

Our study reveals the multifaceted resistance and virulence profiles of CRKP in bloodstream infections and highlights the potential clinical value of berberine hydrochloride as an adjunctive therapeutic agent. These findings support further clinical investigations into incorporating traditional Chinese medicine to improve outcomes in patients with CRKP bloodstream infections.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Zhejiang Chinese Medical University (CN)
No poverty
Openalex Percentile: Top 5%
Antibiotic Resistance in Bacteria
4.73
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