Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pathway
LD significantly reduced coughs and airway inflammation in the CVA guinea pig model by regulating TRPA1, TRPV1, SP, regulatory T cell/T helper 17 cell balance, and the JAK1/STAT6 signaling pathway. These effects were comparable to BUD, suggesting that LD may be a viable alternative treatment for CVA.
Authors
- Fengyi He
- Shiqing Yuan (ORCID: https://orcid.org/0000-0003-1711-7582)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-6325-8557)
- Jingyi Tang (ORCID: https://orcid.org/0000-0001-5560-1223)
- Xuannan Chen
- Yu Lai
Institutions
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1080/02770903.2025.2472357
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16