Sex Differences in the Association between Social Support and Major Depression: A Mediation Analysis with Interoception Mediator
The female depressed patients receive significantly less social support than male counterparts, contributing to more severe symptoms, with the quality and adequacy of social support being crucial due to its mediation by interoception, highlighting a biological mechanism behind MDD. Differences in how interoception mediating role between genders suggest a physiological reason for the heightened severity of depressive symptoms in females.
Authors
- Zhenhe Zhou (ORCID: https://orcid.org/0000-0002-1334-8335)
- Hongliang Zhou (ORCID: https://orcid.org/0000-0002-6496-3346)
- Meichen Lu
- Yunhua Sun (ORCID: https://orcid.org/0009-0006-9554-401X)
- Yamin Wu (ORCID: https://orcid.org/0000-0003-4801-894X)
- Xiaohong Liu (ORCID: https://orcid.org/0000-0001-9317-359X)
Institutions
- Jiangnan University (CN)
- Wuxi Fourth People's Hospital (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- ALPHA PSYCHIATRY
- Published
- 2025-02-28
- DOI
- https://doi.org/10.31083/ap38763
- Primary Topic
- Psychosomatic Disorders and Their Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00