A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children

To this day, there is no Class I (A) evidence base that could serve as a guideline for the treatment of tumor-associated hydrocephalus in children. Tumors of the posterior cranial fossa (PCF), due to their special interaction with the cerebrospinal fluid pathways, are most often accompanied by the development of hydrocephalus. It is debatable which treatment tactics should be applied correctly: whether to install an external ventricular drainage or a ventriculoperitoneal shunt, whether to perform an endoscopic triventriculostomy, or postpone the procedure of cerebrospinal fluid removal until resection of the tumor. This does not exclude the progression of post-resection hydrocephalus, which occurs in 37 % of cases in the pediatric population.

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Publication Details

Journal
Russian Journal for Personalized Medicine
Published
2025-03-07
DOI
https://doi.org/10.18705/2782-3806-2025-5-1-87-93
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children

M. S. Nikolaenko, Konstantin Samochernykh, N. K. Samochernykh, A. Yu. Voevodkina
Russian Journal for Personalized Medicine
Glioma Diagnosis and Treatment
article

A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children

M. S. Nikolaenko, Konstantin Samochernykh, N. K. Samochernykh, A. Yu. Voevodkina
article en

Abstract

To this day, there is no Class I (A) evidence base that could serve as a guideline for the treatment of tumor-associated hydrocephalus in children. Tumors of the posterior cranial fossa (PCF), due to their special interaction with the cerebrospinal fluid pathways, are most often accompanied by the development of hydrocephalus. It is debatable which treatment tactics should be applied correctly: whether to install an external ventricular drainage or a ventriculoperitoneal shunt, whether to perform an endoscopic triventriculostomy, or postpone the procedure of cerebrospinal fluid removal until resection of the tumor. This does not exclude the progression of post-resection hydrocephalus, which occurs in 37 % of cases in the pediatric population.

Russian Journal for Personalized MedicineVol. 5(1)
Federal Almazov North-West Medical Research Centre (RU)
Openalex Percentile: Top 94%
Glioma Diagnosis and Treatment
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A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children — M. S. Nikolaenko, Konstantin Samochernykh, et al. · Russian Journal for Personalized Medicine (2025) | TGRS Research Map | TGRS