Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry
We demonstrate that real-world implementation of the OCS for DBD donors (using predominantly a dedicated recovery team) is associated with expanded donor criteria, longer transport distance, and excellent posttransplantation outcomes. In OCS-DCD donors, outcomes parallel those of donors recovered with NRP-DCD and compare favorably with DBD donor organs.
Authors
- Liviu Klein (ORCID: https://orcid.org/0000-0002-0547-1480)
- David A. D’Alessandro (ORCID: https://orcid.org/0000-0001-9693-7313)
- Victor Pretorius (ORCID: https://orcid.org/0000-0001-6360-4002)
- Koji Takeda (ORCID: https://orcid.org/0000-0001-8263-1911)
- Farhan Zafar (ORCID: https://orcid.org/0000-0003-1803-7242)
- R. Malyala
- Jay D. Pal (ORCID: https://orcid.org/0000-0001-5208-2771)
- Lucian A. Durham (ORCID: https://orcid.org/0000-0001-9939-8589)
- Maryjane Farr (ORCID: https://orcid.org/0000-0003-1066-9368)
- Dan M. Meyer (ORCID: https://orcid.org/0000-0002-2029-1795)
- Yasuhiro Shudo (ORCID: https://orcid.org/0000-0002-4545-1273)
- Masashi Kai (ORCID: https://orcid.org/0000-0003-0605-095X)
- Anelechi Anyanwu
- Andrew Shaffer (ORCID: https://orcid.org/0000-0002-7089-3241)
- Celeste T. Williams (ORCID: https://orcid.org/0000-0001-8150-3520)
- Eric Skipper
- F. Esmailian
- David Kaczorowski
- Sean Pinney (ORCID: https://orcid.org/0000-0002-0268-7817)
- Mandeep R. Mehra (ORCID: https://orcid.org/0000-0001-8683-7044)
- Josef Stehlik (ORCID: https://orcid.org/0000-0002-7362-0513)
- Masaki Funamoto (ORCID: https://orcid.org/0000-0002-0091-6671)
- Akinobu Itoh (ORCID: https://orcid.org/0000-0002-3049-3411)
- John S. Ikonomidis (ORCID: https://orcid.org/0000-0002-1540-7167)
- Benjamin Sun (ORCID: https://orcid.org/0000-0003-4994-5833)
- Arman Kilic (ORCID: https://orcid.org/0000-0001-8112-8345)
- Carmelo A. Milano (ORCID: https://orcid.org/0000-0001-8678-3226)
- Nasir Sulemanjee (ORCID: https://orcid.org/0000-0001-6715-4221)
- Parag C. Patel (ORCID: https://orcid.org/0000-0002-2761-5895)
- Lucian Lozonschi (ORCID: https://orcid.org/0000-0003-2205-3229)
- Suguru Ohira (ORCID: https://orcid.org/0000-0003-0247-865X)
- Mani A. Daneshmand (ORCID: https://orcid.org/0000-0002-0191-9911)
- Mauricio A. Villavicencio (ORCID: https://orcid.org/0000-0003-1080-9471)
- Peter J. Gruber (ORCID: https://orcid.org/0000-0002-7356-905X)
- Jacob N. Schroder (ORCID: https://orcid.org/0000-0001-5836-7284)
- Jonathan W. Haft
- Xiang Zhou (ORCID: https://orcid.org/0000-0001-9635-8741)
- Daniel J. Goldstein (ORCID: https://orcid.org/0000-0002-6519-4809)
- Christopher T. Salerno (ORCID: https://orcid.org/0000-0002-0376-129X)
- Duc Thinh Pham (ORCID: https://orcid.org/0000-0003-4443-601X)
- Ashish S. Shah (ORCID: https://orcid.org/0000-0002-3375-7865)
- Gregory S. Couper
Institutions
- Cedars-Sinai Medical Center (US)
- Brigham and Women's Hospital (US)
- Tufts Medical Center (US)
- Fairview Health Services (US)
- Beth Israel Deaconess Medical Center (US)
- Abbott Northwestern Hospital (US)
- Westchester Medical Center (US)
- Yale New Haven Hospital (US)
- Mayo Clinic (US)
- Montefiore Medical Center (US)
- NewYork–Presbyterian Hospital (US)
- University of Kentucky (US)
- Medical University of South Carolina (US)
- University of Utah (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Emory University Hospital (US)
- Jacksonville College (US)
- Lexington VA Health Care System (US)
- University of Washington Medical Center (US)
- Tampa General Hospital (US)
- Carolinas Medical Center (US)
- Baylor University Medical Center (US)
- Henry Ford Hospital (US)
- University of California San Diego (US)
- University of Chicago Medical Center (US)
- Massachusetts General Hospital (US)
- Northwestern Memorial Hospital (US)
- Andover Eye Associates (US)
- Mount Sinai Medical Center (US)
- Southwestern Medical Center (US)
- Stanford Health Care (US)
- University of California San Francisco Medical Center (US)
- Aurora St. Luke's Medical Center (US)
- Ann Arbor VA Medical Center (US)
- University of North Carolina Hospitals (US)
- Community Health Systems - Lutheran Hospital (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic Hospital (US)
- Methodist Children’s Hospital (US)
- Methodist Hospital (US)
- University of Pittsburgh Medical Center (US)
- University of Minnesota Medical Center (US)
- Mayo Clinic in Florida (US)
- Duke University Hospital (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Circulation
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1161/circulationaha.124.071743
- Citations
- 26
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 52.17