Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations

Emphasizing the spatial molecular pattern behind blood-brain barrier disruption and loss of the vascular tone in the acute phase following ischemic stroke reperfusion suggests the gene expression contribution for a therapeutic target in ischemia-reperfusion abnormalities.

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Publication Details

Journal
Stroke
Published
2025-03-07
DOI
https://doi.org/10.1161/strokeaha.124.048085
Citations
11
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
9.26
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article

Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations

Christian Staehr, Dmitry D. Postnov, Joanna Kalucka, T Pedersen et al.
11 citations
Stroke
Neuroinflammation and Neurodegeneration Mechanisms
9.26
article

Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations

Christian Staehr, Dmitry D. Postnov, Joanna Kalucka, T Pedersen, Vibeke Secher Dam, Halvor Guldbrandsen, Vladimir V. Matchkov, Line Mathilde Brostrup Hansen, Hans Christian Beck, Lin Lin
article en
11 citations

Abstract

Emphasizing the spatial molecular pattern behind blood-brain barrier disruption and loss of the vascular tone in the acute phase following ischemic stroke reperfusion suggests the gene expression contribution for a therapeutic target in ischemia-reperfusion abnormalities.

StrokeVol. 56(4)
University of Southern Denmark (DK), Aarhus University (DK), Odense University Hospital (DK), Maine Farmland Trust (US)
Good health and well-being
Openalex Percentile: Top 2%
Neuroinflammation and Neurodegeneration Mechanisms
9.26
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Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations — Christian Staehr, Dmitry D. Postnov, et al. · Stroke (2025) | TGRS Research Map | TGRS