Implications of reference equations for interpretation of spirometry in three African countries: a cross-sectional study
Reference equations have clinical and public health implications that demand careful consideration, particularly in resource-constrained environments. Use of GLI Global may result more people being identified as having lung function impairment. Further work that includes clinical outcomes is needed to ensure that GLI Global is globally representative. The key limitation of this work is the potential for people with undiagnosed respiratory disease to have been included in the analysis.
Authors
- Denise Banze (ORCID: https://orcid.org/0000-0001-5731-9440)
- Olena Ivanova (ORCID: https://orcid.org/0000-0002-8276-7891)
- Alfred Mfinanga (ORCID: https://orcid.org/0009-0003-2235-554X)
- Leyla Larsson (ORCID: https://orcid.org/0000-0003-4869-4630)
- Katherine Fielding (ORCID: https://orcid.org/0000-0002-6524-3754)
- Celina Nhamuave
- John Robert Hurst (ORCID: https://orcid.org/0000-0002-7246-6040)
- Celso Khosa (ORCID: https://orcid.org/0000-0001-6701-4202)
- Claire Calderwood (ORCID: https://orcid.org/0000-0002-1926-7464)
- Rashida A. Ferrand (ORCID: https://orcid.org/0000-0002-7660-9176)
- Edson Marambire (ORCID: https://orcid.org/0000-0001-5944-5010)
- Norbert Heinrich
- Lilian Tina Minja (ORCID: https://orcid.org/0000-0002-9597-0207)
- Katharina Kranzer
- Akanksha Mimi Malhotra (ORCID: https://orcid.org/0000-0002-5312-7086)
- Andrea Rachow (ORCID: https://orcid.org/0000-0003-4729-3405)
- Lindsay Zurba
Institutions
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- London School of Hygiene & Tropical Medicine (GB)
- Biomedical Research and Training Institute (ZW)
- Fraunhofer Institute for Translational Medicine and Pharmacology (DE)
- German Center for Infection Research (DE)
- Instituto Nacional de Saúde (MZ)
- National Institute for Medical Research (TZ)
- University College London (GB)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1183/23120541.00932-2024
- Citations
- 2
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Deutsches Zentrum für Infektionsforschung
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership