Metformin therapy modifies corneal neuroimmune abnormalities in people with type 2 diabetes
Metformin treatment is associated with superior corneal nerve parameters and neuroimmune tone in the corneal sub-basal nerve plexus. This study provides further evidence that metformin may be neuroprotective in diabetic peripheral neuropathy.
Authors
- Tushar Issar (ORCID: https://orcid.org/0000-0002-8323-6048)
- Arun V. Krishnan (ORCID: https://orcid.org/0000-0001-8883-8825)
- Maria Markoulli (ORCID: https://orcid.org/0000-0002-9227-5866)
- Shyam Sunder Tummanapalli (ORCID: https://orcid.org/0000-0002-2114-1422)
- Roshan Dhanapalaratnam
- Ann M. Poynten (ORCID: https://orcid.org/0000-0002-4373-6881)
- Amy T. Tsoi
- Kerry–Lee Milner
- J. Sng
Institutions
- UNSW Sydney (AU)
- Prince of Wales Hospital (AU)
Publication Details
- Journal
- Diabetologia
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1007/s00125-025-06399-2
- Citations
- 4
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 7.51
Funders
- Johns Hopkins University
- University of New South Wales