Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes Attenuates Experimental Periodontitis in Mice Partly by Delivering miRNAs
These results suggest that exo@H provides protection against periodontitis partly by delivering miRNAs to periodontal tissue. Our results confirm the feasibility of the exo@H delivery platform we constructed and the effectiveness of its use for periodontitis treatment, and this study provides a promising approach for the treatment of periodontitis via miRNA.
Authors
- Ning Guan (ORCID: https://orcid.org/0000-0002-8071-5334)
- Ke Li (ORCID: https://orcid.org/0000-0001-5489-1919)
- Yanan Zhu (ORCID: https://orcid.org/0000-0003-3415-5054)
- Jinlei Wang (ORCID: https://orcid.org/0000-0001-5564-7344)
- Xiaoli Gu (ORCID: https://orcid.org/0000-0002-1437-6928)
- Linyuan Wang (ORCID: https://orcid.org/0000-0002-9015-8033)
Institutions
- Jinzhou Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s502192
- Citations
- 10
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 8.06