Nocturnal respiratory support with nasal high flow in hypercapnic COPD: a randomised, crossover trial
Nocturnal NHF attenuated an increase of <i>P</i> <sub>tcCO<sub>2</sub></sub> during sleep in hypercapnic COPD patients without a relevant effect on sleep quality compared with LTOT. During wakefulness, <i>P</i> <sub>tcCO<sub>2</sub></sub> was unaffected, but <i>V</i>'<sub>E</sub> and RR were reduced, indicating a different physiological response during wakefulness compared with sleep.
Authors
- Mohamed H. Khalaf (ORCID: https://orcid.org/0000-0002-3323-2698)
- U Domanski
- Maik Schroeder (ORCID: https://orcid.org/0000-0002-1794-2710)
- Stanislav Tatkov (ORCID: https://orcid.org/0000-0002-2064-0481)
- Georg Nilius
Institutions
- Witten/Herdecke University (DE)
- Helios Klinik Hagen Ambrock (DE)
- Klinikum Dortmund (DE)
- Fisher & Paykel Healthcare (New Zealand) (NZ)
- Kliniken Essen-Mitte (DE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1183/23120541.01063-2024
- Citations
- 2
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Fisher and Paykel Healthcare