Protein profiling in intensive care unit-treated COVID-19 patients identifies biomarkers of residual lung abnormalities
Despite functional and radiological improvements following COVID-19, persistent upregulation of inflammation and remodelling factors were observed. Similarities in the expression of LAMP3 in COVID-19 and idiopathic pulmonary fibrosis may suggest it as a potential biomarker for chronic lung damage.
Authors
- Göran Dellgren (ORCID: https://orcid.org/0000-0003-4961-9704)
- Malin Nygren‐Bonnier (ORCID: https://orcid.org/0000-0001-6731-8468)
- Åsa M. Wheelock (ORCID: https://orcid.org/0000-0002-8013-2745)
- Dimitrios Kalafatis (ORCID: https://orcid.org/0000-0003-2917-5093)
- Mikael Björnson (ORCID: https://orcid.org/0009-0003-2372-1011)
- Judith Bruchfeld (ORCID: https://orcid.org/0000-0001-5399-0982)
- Linda Elowsson (ORCID: https://orcid.org/0000-0002-0457-0188)
- Anna Kistner (ORCID: https://orcid.org/0000-0002-7942-3211)
- Gunilla Westergren‐Thorsson (ORCID: https://orcid.org/0000-0001-5327-8805)
- Michael Runold (ORCID: https://orcid.org/0000-0001-7568-2278)
- Magnus Sköld
- Barbora Svobodová
Institutions
- Karolinska University Hospital (SE)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1183/23120541.00981-2024
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Crafoordska Stiftelsen
- Hjärt-Lungfonden
- Vetenskapsrådet
- Kungliga Fysiografiska Sällskapet i Lund
- Stiftelsen för Strategisk Forskning
- Medicinska Fakulteten, Lunds Universitet