PD-1<sup>IR2</sup> promotes tumor evasion via deregulating CD8<sup>+</sup> T cell function
PD-1<sup>IR2</sup> is a potential immune checkpoint that may mediate potential resistance to immune checkpoint therapy.
Authors
- Chang Huang (ORCID: https://orcid.org/0000-0002-9782-9880)
- Haojing Zang (ORCID: https://orcid.org/0009-0000-5545-3603)
- Shuwen Cheng (ORCID: https://orcid.org/0000-0002-0365-7935)
- Liqiang Duan (ORCID: https://orcid.org/0000-0002-2566-1687)
- Hongbo Hu (ORCID: https://orcid.org/0000-0002-8177-7641)
- Shan Gao (ORCID: https://orcid.org/0000-0003-0262-4549)
- Xiaodong Wang (ORCID: https://orcid.org/0000-0002-5617-3627)
- Chang Zhang (ORCID: https://orcid.org/0000-0002-3930-9799)
- Fang Guo (ORCID: https://orcid.org/0000-0002-0426-7752)
- Facai Yang (ORCID: https://orcid.org/0000-0002-8402-5488)
- Yinmin Gu (ORCID: https://orcid.org/0000-0001-9825-5447)
- Tongfeng Liu
- Xiaofeng Zhu (ORCID: https://orcid.org/0009-0000-1745-2271)
- Xujie Zhao
- Xuetong Wang (ORCID: https://orcid.org/0009-0002-2378-8585)
Institutions
- University of Science and Technology of China (CN)
- Guiyang Medical University (CN)
- Shanxi Medical University (CN)
- Guizhou University (CN)
- Sichuan University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Zhongda Hospital Southeast University (CN)
- Shanxi Academy of Building Research (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- State Key Laboratory of Biotherapy
- Southeast University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1136/jitc-2024-010529
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province