Efficacy of natalizumab in secondary progressive multiple sclerosis: analysis of two phase III trials

After accounting for therapeutic lag and differences between ASCEND and SPECTRIMS trials, natalizumab, compared with interferon β-1a, reduces disability progression during secondary progressive multiple sclerosis.

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Publication Details

Journal
Journal of Neurology Neurosurgery & Psychiatry
Published
2025-03-06
DOI
https://doi.org/10.1136/jnnp-2024-335495
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of natalizumab in secondary progressive multiple sclerosis: analysis of two phase III trials

Tomáš Kalinčík, Izanne Roos, Winston Dzau
Journal of Neurology Neurosurgery & Psychiatry
Multiple Sclerosis Research Studies
article

Efficacy of natalizumab in secondary progressive multiple sclerosis: analysis of two phase III trials

Tomáš Kalinčík, Izanne Roos, Winston Dzau
article en

Abstract

After accounting for therapeutic lag and differences between ASCEND and SPECTRIMS trials, natalizumab, compared with interferon β-1a, reduces disability progression during secondary progressive multiple sclerosis.

Journal of Neurology Neurosurgery & PsychiatryVol. 96(10)
The Royal Melbourne Hospital (AU), The University of Melbourne (AU)
Openalex Percentile: Top 94%
Multiple Sclerosis Research Studies
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Efficacy of natalizumab in secondary progressive multiple sclerosis: analysis of two phase III trials — Tomáš Kalinčík, Izanne Roos, et al. · Journal of Neurology Neurosurgery & Psychiatry (2025) | TGRS Research Map | TGRS