Statin Drugs Are Associated With Response to Immune Checkpoint Blockade in Recurrent/Metastatic Head and Neck Cancer
Statin therapy appears to be an independent predictor of response to ICB in HNSCC. Larger, prospective studies are needed to determine whether specific statin drugs can improve survival outcomes in ICB-treated patients.
Authors
- Marin Abousaud (ORCID: https://orcid.org/0000-0003-1829-0731)
- Dong M. Shin (ORCID: https://orcid.org/0000-0002-8245-4174)
- Tyler J. Kristoff (ORCID: https://orcid.org/0000-0001-7224-7123)
- Nabil F. Saba (ORCID: https://orcid.org/0000-0003-4972-1477)
- Sean Evans (ORCID: https://orcid.org/0000-0002-3903-2363)
- Nicole C. Schmitt (ORCID: https://orcid.org/0000-0002-0571-3531)
- Subir Goyal (ORCID: https://orcid.org/0000-0003-1737-7771)
- Pranay Nayi
- Yuan Liu (ORCID: https://orcid.org/0000-0001-6227-024X)
- Conor E. Steuer
Institutions
- Emory University (US)
- Children's Healthcare of Atlanta (US)
- Astellas Pharma (United States) (US)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/cam4.70718
- Citations
- 3
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Institute on Deafness and Other Communication Disorders