Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker

Plasma proteomic analysis reveals that high expression of SVEP1 is a risk factor for exfoliation glaucoma, which potentially affects diabetes and is affected by estradiol or LOXL1-AS1. However, further research is needed to establish causality.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-03-07
DOI
https://doi.org/10.1167/iovs.66.3.19
Citations
1
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
1.71
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article

Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker

Aizezi Wumaier, Wenyong Huang, Yizhen Tang, Lingling Xie et al.
1 citations
Investigative Ophthalmology & Visual Science
Glaucoma and retinal disorders
1.71
article

Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker

Aizezi Wumaier, Wenyong Huang, Yizhen Tang, Lingling Xie, Yuncheng Ma, Yuxian He, Shicheng Guo, Mireayi Aizezi, Xin Ma, Wei Wang, Dan Zhang, Xu Zhang, Xinbo Gao, Chao Tang, Jiayong Li, Shufen Zheng, Kaichen Zhuo, Guzainuer Muhetaer
article en
1 citations

Abstract

Plasma proteomic analysis reveals that high expression of SVEP1 is a risk factor for exfoliation glaucoma, which potentially affects diabetes and is affected by estradiol or LOXL1-AS1. However, further research is needed to establish causality.

Investigative Ophthalmology & Visual ScienceVol. 66(3)
Beijing Tongren Hospital (CN), Sun Yat-sen University (CN), Capital Medical University (CN), Fudan University (CN), Chongqing Maternal and Child Health Hospital (CN), Children's Hospital of Zhejiang University (CN), ORCID (US), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Zero hunger
Openalex Percentile: Top 21%
Glaucoma and retinal disorders
1.71
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Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker — Aizezi Wumaier, Wenyong Huang, et al. · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS