Bioinformatics analysis of differentially expressed genes in hyperplastic scars using microarray data

The mRNA expression profile of human HTS samples showed significant changes compared to normal skin samples. TGF-β1, SMAD2, SMAD7, BAX, IGF2, COL1A1, COL1A2, MMPs, CDC14A, ITGB6, EGF, CDKN1C, CDKN2A, CTNNA3, HOXA3 and other related genes involved in biological processes, molecular functions, signaling pathways may be closely related to the occurrence and development of hypertrophic scars.

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Publication Details

Journal
Nucleosides Nucleotides & Nucleic Acids
Published
2025-03-07
DOI
https://doi.org/10.1080/15257770.2025.2466427
Citations
1
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
2.00
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article

Bioinformatics analysis of differentially expressed genes in hyperplastic scars using microarray data

Chun Xiang, Jiayue Ding
1 citations
Nucleosides Nucleotides & Nucleic Acids
Dermatologic Treatments and Research
2.00
article

Bioinformatics analysis of differentially expressed genes in hyperplastic scars using microarray data

Chun Xiang, Jiayue Ding
article en
1 citations

Abstract

The mRNA expression profile of human HTS samples showed significant changes compared to normal skin samples. TGF-β1, SMAD2, SMAD7, BAX, IGF2, COL1A1, COL1A2, MMPs, CDC14A, ITGB6, EGF, CDKN1C, CDKN2A, CTNNA3, HOXA3 and other related genes involved in biological processes, molecular functions, signaling pathways may be closely related to the occurrence and development of hypertrophic scars.

Nucleosides Nucleotides & Nucleic AcidsVol. 45(4)
Quzhou City People's Hospital (CN), Lishui City People's Hospital (CN)
Openalex Percentile: Top 17%
Dermatologic Treatments and Research
2.00
DOISourceOpenAlex
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