Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs
The integrated metabolomic and transcriptomic analysis suggested that nucleotide metabolism and 1C metabolism may be major metabolic pathways affected by siEMMPRIN in AS mouse BMDMs. Our study contributes to a better understanding of the role of EMMPRIN in AS development.
Authors
- Lingying Wang
- Zulong Xie
- D. Zhang
- Tian‐Long Xia (ORCID: https://orcid.org/0000-0001-5135-4675)
- Yun Zhang (ORCID: https://orcid.org/0000-0003-2773-9086)
- Zhong Li (ORCID: https://orcid.org/0000-0002-1039-7000)
- Zhuo Zeng (ORCID: https://orcid.org/0000-0003-4875-2909)
- Tao Wang (ORCID: https://orcid.org/0000-0003-1225-0173)
- Xing Liang (ORCID: https://orcid.org/0000-0003-4406-0753)
- Guozhu Chen (ORCID: https://orcid.org/0000-0002-5069-6312)
- Linfeng Zou (ORCID: https://orcid.org/0000-0002-2607-2075)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-03-07
- DOI
- https://doi.org/10.3389/fmolb.2024.1460186
- Citations
- 3
- Primary Topic
- Signaling Pathways in Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China
- Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission