Plasma esketamine and noresketamine levels and antidepressant response with oral esketamine treatment
In the treatment of depression, clinical response may not correspond to esketamine pharmacokinetic outcomes. Individually-based titration strategies based on clinical antidepressant effects appear to be the optimal approach moving forward.
Authors
- Jolien K. E. Veraart (ORCID: https://orcid.org/0000-0002-9075-4804)
- Jeanine Kamphuis
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Robert A. Schoevers (ORCID: https://orcid.org/0000-0003-0760-9866)
- Sanne Y. Smith-Apeldoorn (ORCID: https://orcid.org/0000-0002-9133-262X)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- European Journal of Pharmacology
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1016/j.ejphar.2025.177470
- Citations
- 1
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- ZonMw