Efficacy of Endoscopic Submucosal Dissection in Gastric Neoplastic Lesions: A Single-Center Experience

Objective: Endoscopic submucosal dissection (ESD) is an endoscopic treatment method that has been indicated as the preferred method for the treatment of early gastric cancer (EGC) and finds increased use in Western countries. This study analyzed the experience of a tertiary center in Türkiye using the ESD methodfor the treatment of gastric neoplastic lesions. Methods: Patients with gastric neoplastic lesions who underwent ESD between March 2019 and March 2023 were included in the study. The rates of en bloc and R0 resection were investigated. The curability of EGC was evaluated according to the current guidelines of the Japan Gastroenterological Endoscopy Society. Patients with a follow-up period of <1 year were excluded from the study. Results: In total, 42 gastric neoplastic lesions from 38 patients were included in the study. The mean tumor diameter was 26.39 mm (range: 10-75 mm). The success rates of en bloc and R0 resection were 97.6% and 90.4%, respectively. Curative resection was achieved in 8/13 (61.5%) patients diagnosed with EGC. The median length of hospital stay was 1 day (range: 1-3 days). Complications occurred postoperatively in 13.1% of the patients. Recurrence was observed in 1 patient (2%) at a median follow-up of 18 months (range: 12-57 months). Conclusion: Endoscopic submucosal dissection is an effective and safe method for treating gastric neoplastic lesions. The rate of curative treatment with the ESD method in EGC should be improved.Cite this article as: Buyruk AM, Baki BE. Efficacy of endoscopic submucosal dissection in gastric neoplastic lesions: A single-center experience. Diagn Interv Endosc. 2024;3(3):44-48.