The associations between circulating amino acids and arterial aneurysms and dissection: A bidirectional Mendelian randomization study

Through bidirectional MR analysis, we found that tyrosine level was negatively correlated with other aneurysms and that aortic dissection reduced circulating glycine. Our findings support a possible interaction between circulating amino acid levels and arterial aneurysms and dissection.

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Publication Details

Journal
International Journal of Cardiology Cardiovascular Risk and Prevention
Published
2025-03-07
DOI
https://doi.org/10.1016/j.ijcrp.2025.200388
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The associations between circulating amino acids and arterial aneurysms and dissection: A bidirectional Mendelian randomization study

Xiaolei Sun, Xiaodong Li, Yarong Ma, Qiu-Lin Jiang et al.
International Journal of Cardiology Cardiovascular Risk and Prevention
Aortic aneurysm repair treatments
article

The associations between circulating amino acids and arterial aneurysms and dissection: A bidirectional Mendelian randomization study

Xiaolei Sun, Xiaodong Li, Yarong Ma, Qiu-Lin Jiang, Huizhi Zhan
article en

Abstract

Through bidirectional MR analysis, we found that tyrosine level was negatively correlated with other aneurysms and that aortic dissection reduced circulating glycine. Our findings support a possible interaction between circulating amino acid levels and arterial aneurysms and dissection.

International Journal of Cardiology Cardiovascular Risk and PreventionVol. 25
King's College London (GB), Southwest Medical University (CN), British Heart Foundation (GB), Affiliated Hospital of Southwest Medical University (CN)
Openalex Percentile: Top 94%
Aortic aneurysm repair treatments
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