Adult pulmonary blastoma

Pulmonary blastoma, a rare and aggressive primary lung tumour, poses diagnostic challenges due to its vague clinical presentation and rarity. Here, we outline the case of a chronic smoker in his 50s presenting with cough and blood-tinged sputum. Radiological assessment revealed a mass lesion in the left upper lobe. Despite inconclusive findings from a conventional Computed Tomography (CTguided biopsy, surgical resection ultimately led to the diagnosis of biphasic pulmonary blastoma. Subsequent histopathological examination and immunohistochemistry (IHC) confirmed the diagnosis, prompting the initiation of adjuvant chemotherapy postoperatively. This case emphasises the importance of thorough diagnostic evaluation, including histopathology and IHC, in guiding treatment decisions for pulmonary blastoma. Furthermore, it highlights the necessity for further research to establish optimal management approaches for this rare malignancy.

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Publication Details

Journal
BMJ Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1136/bcr-2024-263276
Primary Topic
Congenital Diaphragmatic Hernia Studies
Type
article
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article

Adult pulmonary blastoma

Prasanna Kumar T, S P Nirantha, Pragati Rao D, Mohammed Sameer Kundale
BMJ Case Reports
Congenital Diaphragmatic Hernia Studies
article

Adult pulmonary blastoma

Prasanna Kumar T, S P Nirantha, Pragati Rao D, Mohammed Sameer Kundale
article en

Abstract

Pulmonary blastoma, a rare and aggressive primary lung tumour, poses diagnostic challenges due to its vague clinical presentation and rarity. Here, we outline the case of a chronic smoker in his 50s presenting with cough and blood-tinged sputum. Radiological assessment revealed a mass lesion in the left upper lobe. Despite inconclusive findings from a conventional Computed Tomography (CTguided biopsy, surgical resection ultimately led to the diagnosis of biphasic pulmonary blastoma. Subsequent histopathological examination and immunohistochemistry (IHC) confirmed the diagnosis, prompting the initiation of adjuvant chemotherapy postoperatively. This case emphasises the importance of thorough diagnostic evaluation, including histopathology and IHC, in guiding treatment decisions for pulmonary blastoma. Furthermore, it highlights the necessity for further research to establish optimal management approaches for this rare malignancy.

BMJ Case ReportsVol. 18(3)
M.S. Ramaiah Medical College (IN)
Good health and well-being
Openalex Percentile: Top 93%
Congenital Diaphragmatic Hernia Studies
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Adult pulmonary blastoma — Prasanna Kumar T, S P Nirantha, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS